Progesterone-induced changes in sleep in male subjects
This 1997 double-blind, placebo-controlled crossover study investigated the effects of oral progesterone on sleep architecture in nine healthy male volunteers. Administration of 300 mg micronized progesterone at 9:30 PM significantly increased non-REM sleep, particularly stage 2, and decreased slow-wave activity (0.4–4.3 Hz) in EEG recordings. There was also a trend
June 26, 2025
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