This Cochrane Database of Systematic Reviews (2012) systematic review evaluated the effects of long-term hormone therapy (HT) on mortality, cardiovascular outcomes, cancer, gallbladder disease, fractures, and cognition in perimenopausal and postmenopausal women. The review found that long-term HT was associated with an increased risk of stroke and gallbladder disease, while
This Cochrane review analyzed data from 22 studies involving 43,637 perimenopausal and postmenopausal women to assess the long-term effects of hormone therapy (HT). Findings indicate that combined continuous HT increases the risk of coronary events, venous thromboembolism, stroke, breast cancer, gallbladder disease, and lung cancer mortality. Estrogen-only HT was associated
This article reviews the role of menopausal hormone therapy (MHT) in preventing and managing osteoporosis in postmenopausal women. MHT has been shown to reduce bone loss and fracture risk by 20-40%, making it a highly effective treatment option for osteoporosis prevention, particularly in low-risk women. While initial concerns from the
