Well Referenced

Tag: flavonoid

Protoapigenone, a Novel Flavonoid, Inhibits Ovarian Cancer Cell Growth In Vitro and In Vivo

This 2008 study evaluates the anticancer potential of protoapigenone, a naturally occurring flavonoid isolated from fern species, in ovarian cancer models. In vitro, protoapigenone suppressed proliferation and colony formation of ovarian cancer cell lines (MDAH-2774 and SKOV3) by inducing apoptosis and G2/M cell cycle arrest. Mechanistically, it activated stress signaling

Read More »
June 26, 2025 No Comments

Quercetin as a Lyn kinase inhibitor inhibits IgE-mediated allergic conjunctivitis

This study evaluated the effects of quercetin, a plant-derived flavonoid, on IgE-mediated allergic conjunctivitis using both in vitro cell cultures and in vivo mouse models. Quercetin was shown to significantly reduce mast cell degranulation and the release of histamine and inflammatory mediators, resulting in marked improvements in allergic conjunctivitis symptoms.

Read More »
June 26, 2025 No Comments