Pharmacokinetic Evaluation of Intravenous Vitamin C: A Classic Pharmacokinetic Study
This 2022 pharmacokinetic study evaluated intravenous vitamin C (IVC) administration in 21 healthy volunteers and 12 oncology patients, with doses ranging from 1 g to 100 g. The study found that IVC followed first-order kinetics up to 75 g, with C_max values plateauing at 100 g. Nearly complete renal excretion