Tag: experimental autoimmune encephalomyelitis

Methylene blue potentiates stimulus-evoked fMRI responses and cerebral oxygen consumption during normoxia and hypoxia

This study explores the neuroprotective effects of methylene blue (MB) in rats with experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis. The results showed that MB treatment reduced inflammation, oxidative stress, and apoptosis in the brain and spinal cord, significantly improving neurological function. The mechanism of action involves the

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Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis

The study “Alpha Lipoic Acid Inhibits T Cell Migration into the Spinal Cord and Suppresses and Treats Experimental Autoimmune Encephalomyelitis” examined the effects of alpha lipoic acid (ALA) on experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). Administering ALA at doses of 5-100 mg/kg/day significantly reduced disease

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