This retrospective study analyzed 529 overweight and obese patients (BMI ≥25 kg/m²) enrolled in a cardiac rehabilitation and exercise training (CRET) program following major coronary events. Patients were divided based on median weight change: those with greater weight loss (mean -5%) and those with less or no weight loss (mean
This 2016 review article examines the relationship between physical activity and telomere dynamics, highlighting how exercise can prevent telomere shortening—a key marker of biological aging—and reduce the risk of cardio-metabolic diseases. The authors discuss molecular mechanisms by which exercise influences telomere length, including the upregulation of telomerase activity and reduction
This cohort study examined the effects of a 3-month lifestyle modification program on high-sensitivity C-reactive protein (hs-CRP) levels in overweight and obese adults. Participants in the lifestyle group engaged in exercise and received dietary guidance, resulting in significant reductions in weight, total cholesterol, LDL cholesterol, and hs-CRP, as well as
The 2021 study titled “Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men” (PMID: 33123769) explored how long-term exercise affects BCAA metabolism, insulin sensitivity, and liver fat content in sedentary men with and without dysglycaemia. The findings revealed that exercise
This study examined the effects of a 12-month exercise training program and hormone replacement therapy (HRT) on body composition in postmenopausal women. The findings revealed that exercise significantly increased lean soft tissue mass and reduced fat mass, while HRT alone had no notable effect. There were no significant interactions between
