Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase
This study explored how resveratrol interacts with estrogen receptor-β (ER-β) to upregulate mitochondrial superoxide dismutase (MnSOD), leading to inhibited cell growth and enhanced resistance to oxidative stress. The effects were observed across multiple cell lines, including human lung fibroblasts, mouse myoblasts, and human neuroblastoma cells. The study found that the