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Tag: Estrogen-Progestin

Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk

This cohort study evaluated the breast cancer risks associated with menopausal hormone replacement therapy (HRT) in postmenopausal women, comparing estrogen-only therapy to estrogen-progestin therapy. The study found that both estrogen-only and estrogen-progestin therapies increased breast cancer risk, with estrogen-progestin therapy showing a higher risk, particularly in women with lower BMI.

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June 26, 2025 No Comments

Cancer incidence and mortality in women receiving estrogen and estrogen-progestin replacement therapy–long-term follow-up of a Swedish cohort

This study on hormone replacement therapy (HRT) in 22,597 Swedish women found that while HRT did not increase overall cancer mortality, it increased risks of breast and endometrial cancers, especially with estrogen-progestin therapy. However, HRT appeared to offer protection against colon and liver cancers. The findings suggest that the type

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June 26, 2025 No Comments