The role of the immune system in the physiopathology of osteoporosis
This 2012 review examines the interconnection between the immune system and bone metabolism, particularly in the context of osteoporosis. It focuses on the role of immune cells—especially T and B lymphocytes—in promoting osteoclastogenesis through the secretion of pro-inflammatory cytokines such as IL-1, IL-6, and TNF-α. Estrogen deficiency enhances this cytokine