Well Referenced

Tag: Erythrocytosis

A Comparison of Secondary Polycythemia in Hypogonadal Men Treated with Clomiphene Citrate versus Testosterone Replacement: A Multi-Institutional Study

This multi-institutional retrospective study compared the prevalence of secondary polycythemia in 363 hypogonadal men treated with either clomiphene citrate (CC) or testosterone replacement therapy (TRT). The study found that polycythemia occurred in 11.2% of men receiving TRT compared to only 1.7% in the CC group (p = 0.0003). Both treatments

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June 26, 2025 No Comments

The benefits and risks of testosterone replacement therapy: a review

This 2009 review evaluates the benefits and risks of testosterone replacement therapy (TRT) in men with hypogonadism. TRT has been shown to improve libido, sexual function, bone density, muscle mass, body composition, mood, erythropoiesis, cognition, quality of life, and cardiovascular health. However, concerns remain regarding potential adverse effects, including prostate

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June 26, 2025 No Comments

Testosterone replacement therapy in hypogonadal men: assessing benefits, risks, and best practices

This review examines the benefits, risks, and best practices of testosterone replacement therapy (TRT) in hypogonadal men, highlighting improvements in sexual function, mood, bone density, muscle mass, and body composition. While TRT offers significant benefits, potential risks include erythrocytosis, prostate abnormalities, and possible cardiovascular concerns, necessitating careful patient selection and

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June 26, 2025 No Comments

Blood donation and testosterone replacement therapy

This observational study examined the impact of testosterone replacement therapy (TRT) on hemoglobin levels in 39 male blood donors, revealing that 25% of clinic visits recorded hemoglobin levels ≥180 g/L, and 44% of repeat donors had persistently elevated levels. This suggests that blood donation alone may be insufficient to manage

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June 26, 2025 No Comments