Erk pathway Archives - Well Referenced

Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells

This study explores the potential therapeutic benefits of growth hormone-releasing hormone (GHRH) receptor agonists for cardiac stem cells (CSCs) in heart failure treatment. GHRH-R agonists like JI-38, MR-356, and MR-409 were shown to stimulate CSC proliferation and survival, particularly under oxidative stress, by activating key cell signaling pathways (ERK and

June 26, 2025 No Comments

Methylene blue protects dopaminergic neurons against MPTP-induced neurotoxicity by upregulating brain-derived neurotrophic factor

This study investigates the neuroprotective effects of methylene blue (MB) in Parkinson’s disease (PD) models, revealing that MB prevents dopaminergic neuron loss and mitigates dopamine depletion by upregulating brain-derived neurotrophic factor (BDNF) and activating Erk signaling pathways. The results highlight that MB’s protective role is associated with BDNF activation, which

June 26, 2025 No Comments

Tag: Erk pathway

Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells

Methylene blue protects dopaminergic neurons against MPTP-induced neurotoxicity by upregulating brain-derived neurotrophic factor