Reversal of epigenetic aging and immunosenescent trends in humans
The TRIIM (Thymus Regeneration, Immunorestoration, and Insulin Mitigation) trial examined the effects of a one-year intervention using recombinant human growth hormone (rhGH), dehydroepiandrosterone (DHEA), and metformin on epigenetic aging and immune system function in nine healthy men aged 51–65. The study demonstrated a significant reversal in biological age by an
June 26, 2025
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