Tag: epigallocatechin gallate

A Combination Cocktail Improves Spatial Attention in a Canine Model of Human Aging and Alzheimer’s Disease

This experimental study assessed the cognitive effects of a nutraceutical cocktail in aged beagles, an established model for human aging and Alzheimer’s disease. The formulation included turmeric extract (curcuminoids), green tea extract (epigallocatechin gallate), N-acetyl cysteine, R-alpha lipoic acid, and black pepper extract (piperine). Over a 3-month period, treated dogs

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Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation

This 2016 study evaluates the inhibitory effects of epigallocatechin gallate (EGCG), a green tea polyphenol, on cancer stem-like cell (CSC) populations derived from human hepatoma and colon cancer cell lines. CSCs were enriched via sphere formation under nonadherent, serum-free conditions and exhibited higher expression of stemness markers, Nek2, and ATP-binding

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