Tag: enzyme modulation

NAD⁺ Metabolism in Cardiac Health, Aging, and Disease

This comprehensive review examines the pivotal role of NAD⁺ in cardiac physiology, aging, and disease. It details how NAD⁺ levels decline with age, obesity, and hypertension, contributing to cardiovascular diseases. The article discusses mechanisms of NAD⁺ metabolism in cardiomyocytes, including biosynthesis and degradation pathways, and the impact on mitochondrial function

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Multi-target neuroprotective effects of herbal medicines for Alzheimer’s disease

This in vitro study examined the neuroprotective effects of seven traditional medicinal plants—Scutellaria baicalensis, Ginkgo biloba, Hypericum perforatum, Curcuma longa, Lavandula angustifolia, Trigonella foenum-graecum, and Rosmarinus officinalis—in the context of Alzheimer’s disease. Researchers evaluated antioxidant activity, enzyme inhibition related to neurodegeneration (notably GSK-3β), cytotoxicity in brain endothelial and motor neuron

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