NAD⁺ Metabolism in Cardiac Health, Aging, and Disease
This comprehensive review examines the pivotal role of NAD⁺ in cardiac physiology, aging, and disease. It details how NAD⁺ levels decline with age, obesity, and hypertension, contributing to cardiovascular diseases. The article discusses mechanisms of NAD⁺ metabolism in cardiomyocytes, including biosynthesis and degradation pathways, and the impact on mitochondrial function