Well Referenced

Tag: environmental carcinogen

Acute and Chronic Cadmium Exposure Promotes E-Cadherin Degradation in MCF7 Breast Cancer Cells

This study investigates the effects of both acute and chronic cadmium (Cd) exposure on E-cadherin degradation in MCF7 breast cancer cells. The researchers found that Cd exposure leads to the degradation of E-cadherin via the ubiquitination pathway, resulting in reduced E-cadherin/β-catenin complexes and increased nuclear translocation of β-catenin. This translocation

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June 26, 2025 No Comments

The Association Between Urinary Cadmium Levels and Dietary Habits with Risk of Gastrointestinal Cancer in Tabriz, Northwest of Iran

This case-control study investigated the relationship between urinary cadmium (U-Cd) levels, dietary habits, and the risk of gastrointestinal (GI) cancer among 111 patients with GI cancer and 111 healthy controls in Tabriz, Iran. Urinary cadmium concentrations were measured using graphite furnace atomic absorption spectrophotometry. The study found that GI cancer

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June 26, 2025 No Comments

Urinary cadmium concentration and risk of breast cancer: a systematic review and dose-response meta-analysis

This systematic review and meta-analysis evaluated the association between urinary cadmium levels and breast cancer risk. Analyzing data from 2 cohort studies, 5 case-control studies, and 1 cross-sectional study (totaling 1,416 cases and 5,083 controls), the study found that higher urinary cadmium concentrations were associated with increased breast cancer risk.

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June 26, 2025 No Comments