This commentary discusses a study by Stewart et al. (2016) that examined the effects of acute endurance exercise on cardiac function in recreationally active men. Participants performed two cycling trials: 90 minutes at heavy intensity and 120 minutes at moderate intensity. Findings indicated transient reductions in left and right ventricular
This prospective cohort study evaluated 2,377 myocardial infarction (MI) survivors over a mean follow-up of 10.4 years to examine the relationship between exercise volume and cardiovascular mortality. Findings revealed that moderate physical activity (up to 7.2 MET-hours/day) significantly reduced cardiovascular disease (CVD) mortality, with optimal benefits at 5.4–7.2 MET-h/day. However,
This 2016 review article examines the relationship between physical activity and telomere dynamics, highlighting how exercise can prevent telomere shortening—a key marker of biological aging—and reduce the risk of cardio-metabolic diseases. The authors discuss molecular mechanisms by which exercise influences telomere length, including the upregulation of telomerase activity and reduction
