The Aging Bone Marrow and Its Impact on Immune Responses in Old Age
This review examines how aging affects bone marrow (BM) function and its role in maintaining immunological memory. Aging leads to a decline in hematopoietic stem cell function, skewing differentiation towards myeloid over lymphoid lineages, resulting in reduced production of naïve T and B cells. Additionally, the BM microenvironment undergoes changes,
June 26, 2025
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