Well Referenced

Tag: Dyslipidemia

Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review

This 2012 review by Majambu Mbikay evaluates the potential of Moringa oleifera leaves in managing chronic hyperglycemia and dyslipidemia. Preclinical studies indicate that M. oleifera leaf extracts can lower blood glucose levels and improve lipid profiles in diabetic animal models. The mechanisms involve antioxidant properties, enhancement of insulin secretion, and

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June 26, 2025 No Comments

Metabolic and cardiovascular adverse effects associated with antipsychotic drugs

This 2011 review highlights the significant metabolic and cardiovascular risks associated with antipsychotic medications, particularly second-generation antipsychotics like clozapine and olanzapine. These drugs are linked to weight gain, hyperglycemia, dyslipidemia, and metabolic syndrome, increasing the risk of type 2 diabetes and cardiovascular disease. The exact mechanisms remain unclear but may

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June 26, 2025 No Comments

Berberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis

This 2012 systematic review and meta-analysis assessed the efficacy and safety of berberine in managing type 2 diabetes mellitus (T2DM). Analyzing 14 randomized controlled trials involving 1,068 participants, the study found that berberine significantly improved glycemic control and lipid profiles compared to lifestyle modifications or placebo. When compared to standard

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June 26, 2025 No Comments

The Role of Nutraceutical Supplements in the Treatment of Dyslipidemia

This 2012 review by Dr. Mark Houston explores the clinical utility of nutraceutical supplements in the management of dyslipidemia. The paper emphasizes a functional medicine approach combining diet with evidence-based nutraceuticals to reduce LDL cholesterol, LDL particle number, VLDL, and triglycerides, while increasing HDL (especially HDL2b) and LDL particle size.

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June 26, 2025 No Comments

Role of phytochemicals in the management of metabolic syndrome

This review discusses the potential role of various phytochemicals in managing metabolic syndrome (MetS), focusing on their ability to improve components such as dyslipidemia, hypertension, insulin resistance, and obesity. Phytochemicals like soluble fibers, cinnamaldehyde, berberine, and curcumin from sources such as cinnamon, garlic, bitter gourd, and turmeric are highlighted for

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June 26, 2025 No Comments

The Relevance of Dietary Polyphenols in Cardiovascular Protection

This review article explores the cardiovascular protective effects of dietary polyphenols, which are abundant in foods such as grapes, berries, dark chocolate, and tea. These polyphenols have demonstrated antioxidant properties that help mitigate oxidative stress, a key contributor to cardiovascular diseases. The review discusses various studies showing that polyphenols can

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June 26, 2025 No Comments

Obesity, dyslipidemia, and high blood pressure are associated with cardiovascular risk, determined using high-sensitivity C-reactive protein concentration, in young adults

This 2020 observational study published in the Journal of International Medical Research (PMID: 33342336) analyzed 300 young adults in southern Mexico to examine the relationship between high-sensitivity C-reactive protein (hs-CRP) and cardiometabolic risk factors. It found that elevated hs-CRP (>28.57 nmol/L) was strongly associated with obesity (OR = 13.9), high

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June 26, 2025 No Comments

Clinical applications of advanced lipoprotein testing in diabetes mellitus

This review article explores the clinical value of advanced lipoprotein testing in patients with diabetes mellitus, emphasizing that traditional lipid profiles often fail to detect atherogenic subfractions, specifically small, dense LDL particles. Advanced techniques like nuclear magnetic resonance (NMR), gradient gel electrophoresis (GGE), and ultracentrifugation provide greater detail on these

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June 26, 2025 No Comments

Sildenafil citrate for erectile dysfunction in men with diabetes and cardiovascular risk factors: a retrospective analysis of pooled data from placebo-controlled trials

This meta-analysis evaluated the efficacy and safety of sildenafil citrate in men with erectile dysfunction (ED) and diabetes mellitus (DM), including those with additional cardiovascular (CV) risk factors. The study pooled data from 11 randomized, double-blind, placebo-controlled trials involving 974 men with DM and ED, randomized to receive either placebo

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June 26, 2025 No Comments

Testosterone therapy and cardiovascular diseases

This article examines the relationship between testosterone levels, testosterone replacement therapy (TRT), and cardiovascular (CV) health. It highlights that low testosterone is associated with increased risks of diabetes, metabolic syndrome, inflammation, and dyslipidemia and may independently predict higher cardiovascular and all-cause mortality. The review discusses potential benefits of TRT in

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June 26, 2025 No Comments