Effects of the Antidepressant Duloxetine on Body Weight: Analyses of 10 Clinical Studies
This meta-analysis of 10 clinical trials evaluated duloxetine’s impact on body weight in patients with major depressive disorder (MDD). Short-term treatment (8–9 weeks) with duloxetine (40–120 mg/day) resulted in modest weight loss (mean: -0.5 to -0.6 kg), likely due to side effects such as decreased appetite and nausea. Long-term treatment
June 26, 2025
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