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Tag: DNA oxidation

Occupational and lifestyle factors and urinary 8-hydroxydeoxyguanosine

This observational study examined the impact of occupational and lifestyle factors on urinary 8-hydroxydeoxyguanosine (8-OHdG) levels, a biomarker of oxidative DNA damage. Findings indicated that individuals with specific occupational exposures to hazardous substances or certain lifestyle behaviors exhibited higher 8-OHdG concentrations, suggesting increased oxidative stress. Monitoring urinary 8-OHdG provides a

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June 26, 2025 No Comments

Effect of age, smoking and other lifestyle factors on urinary 7-methylguanine and 8-hydroxydeoxyguanosine

This observational study examined the effects of age, smoking, and other lifestyle factors on urinary levels of 7-methylguanine (m7G) and 8-hydroxydeoxyguanosine (8-OHdG), biomarkers of DNA methylation and oxidative DNA damage, respectively. Analyzing 215 healthy Japanese individuals, the study found that current smokers exhibited significantly higher urinary m7G levels (p <

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June 26, 2025 No Comments