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Tag: digital rectal examination

Digital Rectal Examination for Prostate Cancer Screening in Primary Care: A Systematic Review and Meta-Analysis

This 2018 systematic review and meta-analysis evaluated the diagnostic accuracy of digital rectal examination (DRE) for prostate cancer screening in primary care settings. Analyzing data from 7 studies encompassing 9,241 patients, the study found that DRE performed by primary care clinicians had a pooled sensitivity of 0.51 and specificity of

June 26, 2025 No Comments

Occult prostate cancer in men with low serum testosterone levels

This observational study examined the prevalence of occult prostate cancer in 77 men with low serum testosterone levels, normal digital rectal examination (DRE) results, and prostate-specific antigen (PSA) levels of 4.0 ng/mL or less. Prostate cancer was detected in 14% of participants, with prevalence increasing to 29% in men aged

June 26, 2025 No Comments

Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen levels of 4.0 ng/mL or less

This observational study investigated the prevalence of prostate cancer in 345 hypogonadal men with PSA levels of 4.0 ng/mL or less, finding a 15.1% overall cancer detection rate. The prevalence increased with PSA levels, ranging from 5.6% in men with PSA ≤1.0 ng/mL to 36.4% in those with PSA 3.1–4.0

June 26, 2025 No Comments