Well Referenced

Tag: dietary supplementation

Blood Pressure and Metabolic Changes During Dietary L-Arginine Supplementation in Humans

This 2000 single-blind, controlled, crossover dietary intervention study investigated the effects of L-arginine supplementation on blood pressure and metabolic parameters in six healthy volunteers. Participants followed three isocaloric diets for one week each: a control diet, a diet enriched with L-arginine through natural foods, and the control diet supplemented with

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June 26, 2025 No Comments

Pantothenic Acid Deficiency as the Pathogenesis of Acne Vulgaris

This 1995 hypothesis by Dr. L.H. Leung proposes that acne vulgaris stems from a deficiency in pantothenic acid (vitamin B5), essential for synthesizing coenzyme A (CoA). CoA is crucial in fatty acid metabolism and hormone synthesis. A deficiency may impair lipid metabolism, leading to lipid accumulation in sebaceous glands and

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June 26, 2025 No Comments

S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans

This study investigates the effects of S-linolenoyl glutathione (lin-SG) supplementation on lifespan and stress resistance in Caenorhabditis elegans. The supplementation of lin-SG resulted in extended lifespan and increased resistance to oxidative stress, including protection against amyloid-beta and hydrogen peroxide-induced damage. The mechanism behind these benefits involves the upregulation of Sir-2.1,

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June 26, 2025 No Comments

Choline: Exploring the Growing Science on Its Benefits for Moms and Babies

This observational study reviewed the importance of choline intake during pregnancy and lactation, emphasizing its roles in fetal brain development, membrane biosynthesis, neurotransmission, and gene expression. Despite its essential functions, most pregnant women in the U.S. fail to meet the recommended intake of 450 mg/day. Research suggests that adequate choline

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June 26, 2025 No Comments

Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine

This observational study examined the effects of phosphatidylcholine (PC) with different fatty acid compositions on cognitive function and oxidative stress in mice with scopolamine-induced cognitive decline. Mice supplemented with PC rich in EPA (sea cucumber PC) and DHA (squid PC) showed significant improvements in learning and memory performance, reduced acetylcholinesterase

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June 26, 2025 No Comments

Effects of prolonged oral supplementation with l-arginine on blood pressure and nitric oxide synthesis in preeclampsia

This randomized controlled trial examined the effects of prolonged oral supplementation with l-arginine on blood pressure and nitric oxide (NO) synthesis in preeclamptic women. Conducted with 61 participants, the study found that those receiving 3 grams of l-arginine daily for three weeks experienced significant reductions in systolic (134.2 ± 2.9

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June 26, 2025 No Comments