Platelet-rich fibrin matrix for improvement of deep nasolabial folds
This 2010 study evaluated the efficacy of a single injection of autologous platelet-rich fibrin matrix (PRFM) for correcting deep nasolabial folds (NLFs). Fifteen adults received PRFM injections prepared using the Selphyl system. Assessments using the Wrinkle Assessment Scale (WAS) and Global Aesthetic Improvement Scale showed significant improvements: mean WAS scores
June 26, 2025
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