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Tag: dendritic cells

Vitamin A and D in allergy: from experimental animal models and cellular studies to human disease

This 2018 review explores the immunomodulatory roles of vitamins A and D in allergic diseases. Animal studies indicate that deficiencies in these vitamins exacerbate allergic symptoms and lung inflammation, while supplementation, particularly with vitamin D, can attenuate these effects. Active metabolites—retinoic acid (RA) from vitamin A and 1,25-dihydroxyvitamin D3 (VD3)

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June 26, 2025 No Comments

Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals

This preclinical study evaluated the efficacy of convection-enhanced delivery (CED) of bevacizumab, alone or combined with irinotecan, in murine models bearing intracranial gliomas (U87 and U251 cell lines). CED-treated mice demonstrated a 30% longer survival compared to those receiving intravenous (IV) bevacizumab. The combination of CED bevacizumab and intraperitoneal irinotecan

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June 26, 2025 No Comments