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Tag: cortical spreading depression

Role of magnesium in the pathogenesis and treatment of migraines

This 1998 review explores magnesium’s role in migraine pathogenesis and treatment. Magnesium deficiency may contribute to migraines by promoting cortical spreading depression, altering neurotransmitter release, and enhancing platelet aggregation. Clinical studies indicate that intravenous magnesium can provide rapid relief during acute migraine attacks, while oral supplementation may serve as a

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June 26, 2025 No Comments

Why All Migraine Patients Should Be Treated With Magnesium

This article emphasizes the critical role of magnesium in migraine management, advocating for its routine use in all migraine patients due to its potential to reduce migraine frequency and intensity. Magnesium is involved in several processes that may influence migraine pathogenesis, including cortical spreading depression, platelet aggregation, and serotonin receptor

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June 26, 2025 No Comments