Tag: Conjugated Equine Estrogen

Estrogen-alone therapy and invasive breast cancer incidence by dose, formulation, and route of delivery: findings from the WHI observational study

This 2018 analysis from the Women’s Health Initiative Observational Study evaluated the relationship between estrogen-alone hormone therapy and invasive breast cancer incidence among 26,525 postmenopausal women with a hysterectomy. Over an average follow-up of 8.2 years, the study found no significant differences in breast cancer risk when comparing low-dose (

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Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women’s Health Initiative Randomized Clinical Trials

This 2020 study analyzed long-term data from the Women’s Health Initiative (WHI) to assess the impact of menopausal hormone therapy (MHT) on breast cancer incidence and mortality. Among 10,739 women with prior hysterectomy, those receiving conjugated equine estrogen (CEE) alone had a significantly lower breast cancer incidence (HR 0.78; 95%

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Serum estrogen level after hormone replacement therapy and body mass index in postmenopausal and bilaterally ovariectomized women

This observational study examined the relationship between serum estrogen levels after hormone replacement therapy (HRT) and body mass index (BMI) in postmenopausal and bilaterally ovariectomized women. It found that daily HRT administration led to a significant positive correlation between serum estradiol levels and BMI (P < 0.05 and P <

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