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Tag: Congenital Hypogonadotropic Hypogonadism

Efficacy and Outcome Predictors of Gonadotropin Treatment for Male Congenital Hypogonadotropic Hypogonadism: A Retrospective Study of 223 Patients

This retrospective study analyzed 223 azoospermic men with congenital hypogonadotropic hypogonadism (CHH) treated with combined human chorionic gonadotropin (hCG) and human menopausal gonadotropin (hMG) over a median follow-up of 15 months. Results showed that 64% of patients achieved spermatogenesis, with a median time to sperm appearance of 15 months. Significant

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June 26, 2025 No Comments

Increased frequency of anxiety, depression, quality of life and sexual life in young hypogonadotropic hypogonadal males and impacts of testosterone replacement therapy on these conditions

This observational study examined the impact of testosterone replacement therapy (TRT) on anxiety, depression, quality of life, and sexual function in young males with congenital hypogonadotropic hypogonadism (CHH). The study included 39 CHH patients and 40 healthy controls, revealing that CHH patients had significantly higher anxiety and depression levels and

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June 26, 2025 No Comments