Tag: conditioned media

Human Umbilical Cord-Derived Mesenchymal Stem Cells in the Treatment of Multiple Sclerosis Patients: Phase I/II Dose-Finding Clinical Study

This 2024 Phase I/II clinical trial assessed the safety and efficacy of human umbilical cord-derived mesenchymal stem cells (UC-MSCs) in patients with multiple sclerosis (MS). Participants were divided into two groups: Group A received two intrathecal doses of UC-MSCs, while Group B received a single dose. Both groups also received

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Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonary disease

This 2018 review article explores the therapeutic potential of mesenchymal stem/stromal cell (MSC)-derived products, particularly conditioned media (CM) and extracellular vesicles (EVs), in treating pulmonary diseases. MSCs are known for their regenerative and immunomodulatory properties, which are largely mediated through their secretome. The review highlights preclinical studies demonstrating the efficacy

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