Well Referenced

Tag: complementary therapy

The benefits of ascorbate to protect healthy cells in the prevention and treatment of oncological diseases

This review explores the protective role of ascorbate (vitamin C) in oncology, emphasizing its antioxidant properties that safeguard healthy cells from oxidative stress induced by internal and external factors, including chemotherapy and radiotherapy. Ascorbate neutralizes reactive oxygen species, thereby preventing mitochondrial and DNA damage, and modulates immune responses to support

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June 26, 2025 No Comments

Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research

This systematic review evaluated the clinical and preclinical effects of Viscum album L. (European mistletoe) extracts (VAE) in breast and gynaecological cancers. It included 19 randomized controlled trials (RCTs), 16 non-randomized controlled studies, and 11 single-arm cohort studies, encompassing over 9,900 patients. Findings indicated that VAE may improve quality of

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June 26, 2025 No Comments

Prospective Controlled Cohort Studies on Long-Term Therapy of Ovarian Cancer Patients with Mistletoe (Viscum album L.) Extracts Iscador

This 2007 study assessed the impact of long-term Iscador therapy on survival and psychosomatic self-regulation in ovarian cancer patients. It included two randomized matched-pair studies and two non-randomized matched-pair studies, comparing patients receiving Iscador with controls. Results indicated that Iscador therapy might prolong overall survival, particularly in patients with distant

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June 26, 2025 No Comments

Mistletoe as complementary treatment in patients with advanced non-small-cell lung cancer treated with carboplatin-based combinations: a randomised phase II study

This 2013 randomized phase II study evaluated the efficacy and safety of adding mistletoe extract (Iscador) to carboplatin-based chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC). The study found that patients receiving mistletoe extract experienced improved quality of life, including better emotional and functional well-being, compared to those receiving

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June 26, 2025 No Comments

Influence of Complementary Viscum album (Iscador) Administration on Microcirculation and Immune System of Ear, Nose and Throat Carcinoma Patients Treated with Radiation and Chemotherapy

This 2005 clinical trial investigated the effects of adjunctive Viscum album extract (Iscador) therapy on microcirculation and immune function in patients with ear, nose, and throat carcinomas undergoing radiotherapy and chemotherapy. Using vital microscopic and reflection spectrometric imaging, the study assessed microcirculatory parameters and white blood cell immunology before, during,

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June 26, 2025 No Comments

Intravenous Vitamin C Administration Improves Quality of Life in Breast Cancer Patients During Chemo-/Radiotherapy and Aftercare: Results of a Retrospective, Multicentre, Epidemiological Cohort Study in Germany

This 2011 retrospective multicenter cohort study evaluated the safety and efficacy of intravenous vitamin C (IVC) administration in 125 women with breast cancer (UICC stages IIa–IIIb) during the first postoperative year. Fifty-three patients received 7.5 g IVC weekly alongside standard chemo-/radiotherapy, while 72 served as controls. The IVC group experienced

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June 26, 2025 No Comments

Complementary Treatment with Mistletoe Extracts During Chemotherapy: Safety, Neutropenia, Fever, and Quality of Life Assessed in a Randomized Study

This randomized controlled trial evaluated the safety and efficacy of European mistletoe extracts (Helixor A and Iscador M Spez) as complementary therapy during chemotherapy in 95 breast cancer patients (stages T1–T3N0–N2M0). Patients received six cycles of cyclophosphamide, adriamycin, and 5-fluorouracil, with mistletoe extracts administered subcutaneously three times per week over

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June 26, 2025 No Comments

Impact of Intravenous Vitamin C Administration in Reducing Severity of Symptoms in Breast Cancer Patients During Treatment

This single-center, single-blind, randomized controlled trial conducted in Pakistan assessed the effects of intravenous vitamin C (IVC) on symptom severity in 350 breast cancer patients (stages IIA–IIIb) undergoing standard treatment. Participants were randomized to receive either 25g/week of IVC or placebo over four weeks. The IVC group showed statistically significant

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June 26, 2025 No Comments

Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis

This multicenter observational study evaluated the impact of adding Viscum album L. (European mistletoe) extract to standard chemotherapy in 158 patients with stage IV non-small cell lung cancer (NSCLC). Patients were divided into two groups: 108 received chemotherapy alone, while 50 received chemotherapy plus Viscum album L. The median overall

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June 26, 2025 No Comments

Summary of European Mistletoe in Cancer

​European mistletoe (Viscum album) has been used in traditional medicine for various conditions, including cancer, seizures, headaches, and menopause symptoms. In Europe, mistletoe extracts are sold as prescription drugs and are administered via injection. However, the U.S. Food and Drug Administration (FDA) has not approved mistletoe for any medical use.

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June 26, 2025 No Comments