Well Referenced

Tag: cognitive improvement

Are Ketogenic Diets Promising for Alzheimer’s Disease? A Translational Review

This 2020 translational review analyzed 22 studies—11 preclinical and 11 clinical—evaluating the impact of ketogenic diets (KDs) and medium-chain triglyceride (MCT) supplementation on Alzheimer’s disease (AD). Animal studies showed consistent improvements in cognitive and motor outcomes, reductions in amyloid and tau pathology, and enhanced mitochondrial function. Human trials, though varied

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June 26, 2025 No Comments

Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial

This multicenter, double-blind, randomized, placebo-controlled trial evaluated the efficacy and tolerability of choline alfoscerate (CA) in treating cognitive impairment in patients with mild to moderate Alzheimer’s disease (AD). A total of 261 patients were randomized to receive either CA (400 mg capsules) or placebo, three times daily for 180 days.

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June 26, 2025 No Comments

Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women

This observational study examined the impact of estradiol (E2) levels on cognitive function during antidepressant treatment in 39 women with major depressive disorder (MDD), comparing pre-menopausal and post-menopausal groups. Over a 6-week period, cognitive function improved significantly across all participants (P=0.00001), but in post-menopausal women, higher E2 levels were strongly

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June 26, 2025 No Comments