This neuroimaging study assessed how obesity impacts brain structure across the adult lifespan using MRI data from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) cohort. Analyzing 527 individuals aged 20–87, researchers found that overweight and obese adults—especially those in midlife—had significantly reduced white matter volume compared to their lean
This 1995 article examines the evolving therapeutic role of estrogen replacement therapy (ERT) in preventing osteoporosis, heart disease, and cognitive decline in older adults. The study highlights estrogen’s potential benefits in preventing senile dementia and Alzheimer’s disease, as it may act as a growth factor for estrogen-responsive neurons, influence vascular
The review article titled “B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review” by David O. Kennedy, published in Nutrients in 2016 (PMID: 26828517), examines the essential roles of the eight B-vitamins in brain function, highlighting their involvement in energy production, DNA/RNA synthesis and repair, methylation processes, and the
