A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity
This 2003 randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of topiramate (TPM) for weight loss in 385 obese adults aged 18–75. Participants were assigned to receive placebo or TPM at doses of 64, 96, 192, or 384 mg/day, alongside a standardized lifestyle program. After 24 weeks, mean weight
June 26, 2025
No Comments