Tag: clinical diagnostics

Assessment of mitochondrial respiratory chain enzymes in cells and tissues

This review outlines standardized methodologies for assessing mitochondrial respiratory chain enzyme activity, highlighting their diagnostic utility for mitochondrial diseases. By offering consistent protocols and detailing enzymatic assays, the article supports their integration into both clinical and research settings. This enables precise identification of oxidative phosphorylation deficits, improving diagnostic accuracy and

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Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods

This study compared different methods for measuring free testosterone in women, focusing on the accuracy and reliability of equilibrium dialysis, direct radioimmunoassay (RIA), and calculated values using the law of mass action. The results showed that calculated free testosterone values correlated excellently with equilibrium dialysis, making these methods more reliable

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