Glutamine Restores Tight Junction Protein Claudin-1 Expression in Colonic Mucosa of Patients With Diarrhea-Predominant Irritable Bowel Syndrome
The 2016 observational study titled “Glutamine Restores Tight Junction Protein Claudin-1 Expression in Colonic Mucosa of Patients With Diarrhea-Predominant Irritable Bowel Syndrome” (PMID: 25972430) examined the effect of glutamine on tight junction protein expression in IBS-D patients. Using colonic biopsy specimens from 12 patients, researchers incubated tissues with glutamine at
June 26, 2025
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