Natural products – alpha-lipoic acid and acetyl-L-carnitine – in the treatment of chemotherapy-induced peripheral neuropathy
This 2018 review examines the potential of alpha-lipoic acid (ALA) and acetyl-L-carnitine (ALC) in managing chemotherapy-induced peripheral neuropathy (CIPN). ALA’s antioxidant and anti-inflammatory properties have shown promise in preclinical studies, but clinical trials yield mixed results, with efficacy influenced by administration routes. ALC demonstrates benefits in vitro and in animal
June 26, 2025
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