Taurine ameliorates neurobehavioral, neurochemical and immunohistochemical changes in sporadic dementia of Alzheimer’s type (SDAT) caused by intracerebroventricular streptozotocin in rats
This preclinical study evaluated the neuroprotective effects of taurine in a rat model of sporadic Alzheimer’s disease induced by intracerebroventricular (ICV) injection of streptozotocin (STZ). Rats received a single bilateral ICV-STZ injection (3 mg/kg), leading to cognitive deficits, oxidative stress, and cholinergic dysfunction. Taurine was administered orally at 50 mg/kg
June 26, 2025
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