Diagnostic chelation challenge with DMSA: a biomarker of long-term mercury exposure?
This 2001 study evaluated the effectiveness of using dimercaptosuccinic acid (DMSA) chelation challenge as a biomarker for long-term mercury exposure. Researchers administered two doses of DMSA (10 mg/kg) to 119 former chloralkali plant workers with documented mercury exposure and 101 unexposed controls, measuring 24-hour urinary mercury excretion before and after