Sensitive tumour detection and classification using plasma cell-free DNA methylomes
This study introduces cfMeDIP-seq, an immunoprecipitation-based method for analyzing methylation patterns in small quantities of circulating cell-free DNA (cfDNA). By profiling the methylomes of cfDNA from plasma samples, the researchers achieved sensitive detection and accurate classification of various cancer types, including early-stage tumors. The approach leverages large-scale, tissue- and cancer-type-specific
June 26, 2025
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