Pharmacokinetics of glutathione and its metabolites in normal subjects
This observational study investigated the pharmacokinetics of glutathione (GSH) and its metabolites—cysteine (Cys), cystine (Cys2), and methionine (Met)—in healthy individuals to determine optimal dosing for reducing reactive oxygen species (ROS), especially in cases like paraquat poisoning. It found that Cys and Met effectively suppressed ROS production in a dose-dependent manner,