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Tag: cell growth inhibition

Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: role of Sp transcription factors and microRNA-27a:ZBTB10

This study explores the effect of betulinic acid on estrogen receptor-negative (ER-negative) breast cancer cells both in vitro and in vivo. The findings show that betulinic acid inhibits cell growth by regulating Sp transcription factors and microRNA-27a, which in turn affects the expression of ZBTB10, a gene involved in tumor

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June 26, 2025 No Comments

Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase

This study explored how resveratrol interacts with estrogen receptor-β (ER-β) to upregulate mitochondrial superoxide dismutase (MnSOD), leading to inhibited cell growth and enhanced resistance to oxidative stress. The effects were observed across multiple cell lines, including human lung fibroblasts, mouse myoblasts, and human neuroblastoma cells. The study found that the

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June 26, 2025 No Comments