Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system
This 2014 review explores the role of the CD200-CD200R signaling axis in regulating neuroinflammation within the central nervous system (CNS). The interaction between neuronal CD200 and microglial CD200R serves as an inhibitory mechanism to maintain microglial quiescence and prevent excessive inflammatory responses. Disruption of this pathway is implicated in neurodegenerative
June 26, 2025
No Comments