cardiovascular mortality Archives

Increased Cardiovascular Disease Mortality Associated With Excessive Exercise in Heart Attack Survivors

This prospective cohort study evaluated 2,377 myocardial infarction (MI) survivors over a mean follow-up of 10.4 years to examine the relationship between exercise volume and cardiovascular mortality. Findings revealed that moderate physical activity (up to 7.2 MET-hours/day) significantly reduced cardiovascular disease (CVD) mortality, with optimal benefits at 5.4–7.2 MET-h/day. However,

June 26, 2025 No Comments

Blood Lead Below 0.48 μmol/L (10 μg/dL) and Mortality Among US Adults

This large-scale prospective study analyzed data from 13,946 adults in the NHANES III cohort (1988–1994) with up to 12 years of follow-up. It found that even blood lead levels below 0.48 μmol/L (10 μg/dL) were associated with increased all-cause and cardiovascular mortality. Participants in the highest tertile of blood lead

June 26, 2025 No Comments

Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women’s Health Initiative Randomized Trials

This 2017 analysis of the Women’s Health Initiative (WHI) randomized trials examined the long-term effects of menopausal hormone therapy (HT) on mortality. Among 27,347 postmenopausal women followed for a median of 18 years, neither estrogen-alone nor estrogen-plus-progestin therapy was associated with increased all-cause or cause-specific mortality, including deaths from cardiovascular

June 26, 2025 No Comments

Blood-borne biomarkers of mortality risk: systematic review of cohort studies

This systematic review analyzed 23 prospective cohort studies to identify blood-borne biomarkers predictive of mortality risk in adults aged 50–75 years. Out of 51 biomarkers examined, 20 were significantly associated with mortality. Notably, elevated levels of C-reactive protein (CRP) were linked to increased all-cause, cancer, and cardiovascular mortality. Similarly, higher

June 26, 2025 No Comments

Leisure-time running reduces all-cause and cardiovascular mortality risk

This 2014 prospective cohort study analyzed data from 55,137 adults aged 18–100 over a 15-year period to assess the impact of leisure-time running on mortality. Approximately 24% of participants reported running. Compared to non-runners, runners exhibited a 30% lower risk of all-cause mortality and a 45% lower risk of cardiovascular

June 26, 2025 No Comments

Coenzyme Q10 and Heart Failure: A State-of-the-Art Review

The review article examines the role of Coenzyme Q10 (CoQ10) in the management of chronic heart failure (HF), emphasizing its biochemical function in mitochondrial energy production and antioxidant activity. The Q-SYMBIO trial demonstrated that CoQ10 supplementation significantly reduced cardiovascular mortality by 42% (p=0.026) and all-cause mortality by 43% (p=0.036) over

June 26, 2025 No Comments

Well Referenced

Tag: cardiovascular mortality

Increased Cardiovascular Disease Mortality Associated With Excessive Exercise in Heart Attack Survivors

Blood Lead Below 0.48 μmol/L (10 μg/dL) and Mortality Among US Adults

Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women’s Health Initiative Randomized Trials

Blood-borne biomarkers of mortality risk: systematic review of cohort studies

Leisure-time running reduces all-cause and cardiovascular mortality risk

Coenzyme Q10 and Heart Failure: A State-of-the-Art Review