Well Referenced

Tag: cardiotoxicity

Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients

This 2022 randomized, double-blind, placebo-controlled trial investigated the effects of alpha-lipoic acid (ALA) in reducing chemotherapy-induced toxicities in 64 women with breast cancer undergoing treatment with doxorubicin, cyclophosphamide, and paclitaxel. Patients were assigned to receive either ALA (600 mg/day) or placebo for six months. ALA significantly improved chemotherapy-induced peripheral neuropathy

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June 26, 2025 No Comments

Glutamine: A novel approach to chemotherapy-induced toxicity

The 2012 study “Glutamine: A novel approach to chemotherapy-induced toxicity” (DOI: 10.4103/0971-5851.96962) reviews the potential of glutamine supplementation to reduce the adverse effects of chemotherapy, such as mucositis, cardiotoxicity, neurotoxicity, and gastrointestinal damage. The study highlights glutamine’s protective role in supporting immune function, mitigating side effects, and enhancing recovery during

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June 26, 2025 No Comments

Prevention of Chemotherapy and Radiation Toxicity With Glutamine

This review article explores the use of glutamine supplementation to prevent chemotherapy and radiation-induced toxicities in cancer patients. Glutamine was found to reduce the severity and incidence of side effects such as mucositis, diarrhea (especially from irinotecan), peripheral neuropathy (notably from paclitaxel), hepatic veno-occlusive disease, and anthracycline-induced cardiotoxicity. It also

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June 26, 2025 No Comments