Well Referenced

Tag: cancer-related fatigue

Oxygen-ozone therapy as support and palliative therapy in 50 cancer patients with fatigue – A short report

This 2018 short report by Tirelli et al. evaluated the use of oxygen-ozone autohemotherapy (O2-O3-AHT) as a supportive treatment for cancer-related fatigue. Fifty patients with various cancers (breast, lung, colon, renal, prostate, melanoma, hepatocellular carcinoma) received O2-O3-AHT twice weekly for one month, followed by twice-monthly maintenance therapy. Fatigue severity was

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June 26, 2025 No Comments

Targeting inflammation in cancer-related-fatigue: a rationale for mistletoe therapy as supportive care in colorectal cancer patients

This retrospective cohort study evaluated the impact of mistletoe extract (Iscador®Qu) as supportive therapy in 324 patients with non-metastatic colorectal cancer (UICC stage I–III) undergoing adjuvant chemo- or radio-chemotherapy. Over a median treatment period of 8.6 months, patients receiving mistletoe therapy (n=181) exhibited a significantly lower incidence of cancer-related fatigue

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June 26, 2025 No Comments

High-Dose Vitamin C in Advanced-Stage Cancer Patients

This 2021 narrative review examines the use of high-dose intravenous vitamin C (IVC) in advanced-stage cancer patients. While preclinical studies demonstrate that pharmacologic concentrations of ascorbate can exert cytotoxic effects on malignant cells and enhance the efficacy of chemotherapy, clinical evidence in humans remains limited. Some studies suggest that IVC

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June 26, 2025 No Comments

Cancer-related fatigue in patients treated with mistletoe extracts: a systematic review and meta-analysis

This 2022 meta-analysis published in Supportive Care in Cancer examined the effectiveness of mistletoe extract (Viscum album) in alleviating cancer-related fatigue (CRF). Analyzing 12 randomized controlled trials (RCTs) with 1,494 participants and 7 non-randomized studies (NRSIs) with 2,668 participants, the researchers found a moderate reduction in CRF among those treated

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June 26, 2025 No Comments

Impact of Oncological Therapy and Viscum album L Treatment on Cancer-Related Fatigue and Internal Coherence in Nonmetastasized Breast Cancer Patients

This 2020 observational study (Integrative Cancer Therapies, PMID: 32478590) evaluated the impact of add-on Viscum album L. (mistletoe) therapy on cancer-related fatigue, internal coherence, and quality of life in 319 nonmetastasized breast cancer patients over 24 months. While chemotherapy, immunotherapy, and endocrine therapies were associated with worsened fatigue (by 17,

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June 26, 2025 No Comments

Pharmacological Effects of Ginseng: Multiple Constituents and Multiple Actions on Humans

This systematic review explores the diverse pharmacological effects of ginseng, focusing on its active compounds—ginsenosides and polysaccharides—and their impact on human health. Drawing from 20 years of clinical studies, primarily in developed countries, the review highlights ginseng’s adaptogenic properties, which help regulate physiological processes and promote homeostasis. It demonstrates beneficial

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June 26, 2025 No Comments

Analysis of Changes in Cancer-Related Fatigue of Breast Cancer Patients Receiving an Integrative Medicine Program

This observational study evaluated the impact of an integrative medicine program on cancer-related fatigue (CRF) in breast cancer patients. The program included non-pharmacological interventions (NPIs) such as nursing compresses, elaborate consultations and life review (ECLR), exercise therapy, and Viscum album L. extracts. Results showed that chemotherapy worsened CRF, but NPIs,

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June 26, 2025 No Comments

l-carnitine and cancer cachexia: Clinical and experimental aspects

This review article examines the role of L-carnitine in cancer cachexia, a syndrome characterized by muscle wasting, fatigue, weight loss, and reduced appetite in cancer patients. L-carnitine supplementation has been associated with improvements in lean body mass, reduced fatigue, and enhanced overall quality of life, although findings across studies remain

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June 26, 2025 No Comments