Estimation of Solid Tumor Doubling Times from Progression-Free Survival Plots Using a Novel Statistical Approach
This 2019 study presents a novel statistical methodology to estimate tumor doubling times (TDTs) from published progression-free survival (PFS) plots, facilitating better understanding of tumor growth dynamics in solid malignancies. Researchers extracted PFS curves from clinical trials encompassing twelve cancer types, including pancreatic, melanoma, hepatocellular carcinoma, renal cell carcinoma, triple-negative
June 26, 2025
No Comments