Tag: cancer diagnostics

Telomere biology: Rationale for diagnostics and therapeutics in cancer

This 2015 review discusses the pivotal role of telomere biology in cancer development and its potential as a target for diagnostics and therapeutics. It highlights how telomere dysfunction enables malignant transformation by allowing cells to bypass the Hayflick limit, leading to uncontrolled proliferation. The article explores various components involved in

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Lymphocyte glutathione levels in acute leukemia

This observational study investigated lymphocyte glutathione levels in 20 patients with acute leukemia (both AML and ALL) compared to 20 healthy controls to determine its relationship to disease activity and chemotherapy response. Glutathione levels were nearly double in acute myeloid leukemia and 2.5 times higher in acute lymphoid leukemia patients

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