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Tag: CaNa2EDTA

CaNa2EDTA chelation attenuates cell damage in workers exposed to lead–a pilot study

This 2015 pilot study investigated the effects of CaNa₂EDTA chelation therapy on oxidative and genotoxic damage in smelting factory workers with chronic lead exposure averaging 5.8 ± 1.2 years. Following a five-day CaNa₂EDTA regimen, significant reductions were observed in oxidative stress biomarkers, including normalized activities of antioxidant enzymes (Cu,Zn-SOD and

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June 26, 2025 No Comments

Mobilization of heavy metals by newer, therapeutically useful chelating agents

This review examines the effectiveness and safety of four chelating agents—DMSA, DMPS, CaNa₂EDTA, and BAL—for treating heavy metal poisoning, particularly lead, mercury, and arsenic intoxication. The study highlights that DMSA and DMPS are safer and more effective alternatives to traditional chelators like CaNa₂EDTA and BAL, with DMSA primarily used for

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June 26, 2025 No Comments

A comparison of sodium calcium edetate (edetate calcium disodium) and succimer (DMSA) in the treatment of inorganic lead poisoning

This review compares the effectiveness, pharmacokinetics, and adverse effects of sodium calcium edetate (CaNa2EDTA) and succimer (DMSA) for treating inorganic lead poisoning. Both agents are effective in enhancing lead excretion and reducing blood lead levels, with DMSA being more effective in reducing kidney lead concentrations and CaNa2EDTA more effective for

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June 26, 2025 No Comments