Well Referenced

Tag: calprotectin

Lower Diet Quality Associated with Subclinical Gastrointestinal Inflammation in Healthy United States Adults

This 2024 observational study published in the Journal of Nutrition (DOI: 10.1016/j.tjnut.2024.02.030) examined the relationship between diet quality and subclinical gastrointestinal (GI) inflammation in 358 healthy U.S. adults. Researchers found that higher intake of fiber, legumes, vegetables, and fruits—along with better overall diet quality measured by the Healthy Eating Index—was

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June 26, 2025 No Comments

Calprotectin: from biomarker to biological function

This review discusses the multifaceted role of calprotectin (CP) as both a biomarker and an active player in immune modulation and antimicrobial defense. CP is commonly used to assess gastrointestinal inflammation, particularly in inflammatory bowel diseases (IBD), and its concentration can help distinguish between inflammatory and non-inflammatory conditions. The review

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June 26, 2025 No Comments

Calprotectin in inflammatory bowel disease

This review article explores the role of calprotectin as a key biomarker in inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Elevated levels of calprotectin are closely associated with disease activity, making it an effective non-invasive marker for diagnosing IBD, assessing disease severity, monitoring treatment response, and predicting

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June 26, 2025 No Comments

Assessment of Intestinal Permeability and Inflammation Bio-Markers in Patients with Rheumatoid Arthritis

This 2023 observational study published in Nutrients (PMID: 37242269) explored the relationship between intestinal permeability and inflammation in patients with rheumatoid arthritis by analyzing serum and fecal levels of zonulin and calprotectin, as well as plasma lipopolysaccharides (LPS). Among 59 RA patients, findings showed that higher serum zonulin correlated with

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June 26, 2025 No Comments

Review article: Faecal biomarkers for assessing small intestinal damage in coeliac disease and environmental enteropathy

This 2024 systematic review published in Alimentary Pharmacology & Therapeutics (PMID: 39233618) assessed the utility of fecal biomarkers in diagnosing small intestinal damage associated with coeliac disease (CD) and environmental enteropathy (EE). The review analyzed 35 original studies focused on mucosa-derived fecal biomarkers, including calprotectin and antibodies like anti-gliadin, tissue

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June 26, 2025 No Comments