cadmium exposure Archives - Well Referenced

Acute and Chronic Cadmium Exposure Promotes E-Cadherin Degradation in MCF7 Breast Cancer Cells

This study investigates the effects of both acute and chronic cadmium (Cd) exposure on E-cadherin degradation in MCF7 breast cancer cells. The researchers found that Cd exposure leads to the degradation of E-cadherin via the ubiquitination pathway, resulting in reduced E-cadherin/β-catenin complexes and increased nuclear translocation of β-catenin. This translocation

June 26, 2025 No Comments

The Association Between Environmental Cadmium Exposure, Blood Pressure, and Hypertension: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis evaluated the relationship between environmental cadmium (Cd) exposure and blood pressure (BP)/hypertension (HTN) in general populations. The study included literature published between 2000 and April 2021, assessing Cd levels in blood, urine, and hair samples. Findings indicated a positive association between Cd exposure and increased

June 26, 2025 No Comments

Cadmium Exposure and Potential Health Risk from Foods in Contaminated Area, Thailand

This study assessed cadmium (Cd) exposure and associated health risks among residents consuming locally produced foods in a Cd-contaminated area of Thailand. The research involved analyzing Cd concentrations in various food items and estimating dietary Cd intake among the population. Findings indicated that the average daily intake of Cd exceeded

June 26, 2025 No Comments

The Association Between Urinary Cadmium Levels and Dietary Habits with Risk of Gastrointestinal Cancer in Tabriz, Northwest of Iran

This case-control study investigated the relationship between urinary cadmium (U-Cd) levels, dietary habits, and the risk of gastrointestinal (GI) cancer among 111 patients with GI cancer and 111 healthy controls in Tabriz, Iran. Urinary cadmium concentrations were measured using graphite furnace atomic absorption spectrophotometry. The study found that GI cancer

June 26, 2025 No Comments

Cadmium Exposure and Cancer Mortality in a Prospective Cohort: The Strong Heart Study

This prospective cohort study evaluated the association between urinary cadmium (U-Cd) levels and cancer mortality among 3,792 American Indian adults aged 45–74 from Arizona, Oklahoma, and the Dakotas, followed for up to 20 years. Baseline U-Cd concentrations were measured using inductively coupled plasma mass spectrometry. After adjusting for sex, age,

June 26, 2025 No Comments

Urinary cadmium concentration and risk of breast cancer: a systematic review and dose-response meta-analysis

This systematic review and meta-analysis evaluated the association between urinary cadmium levels and breast cancer risk. Analyzing data from 2 cohort studies, 5 case-control studies, and 1 cross-sectional study (totaling 1,416 cases and 5,083 controls), the study found that higher urinary cadmium concentrations were associated with increased breast cancer risk.

June 26, 2025 No Comments

Low-Level Cadmium Exposure and Atherosclerosis

The article “Low-Level Cadmium Exposure and Atherosclerosis” explores the impact of environmental cadmium exposure on cardiovascular health, emphasizing its role as a pro-atherosclerotic risk factor. It discusses cadmium’s toxicity, its effects on cellular activities, and its association with increased cardiovascular disease (CVD) risk. The authors also highlight potential therapeutic benefits

June 26, 2025 No Comments

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