Tag: CAD

State-of-the-Art Updates on Cardiac Computed Tomographic Angiography for Assessing Coronary Artery Disease

This 2015 review article provides an in-depth analysis of the evolution and clinical utility of cardiac computed tomographic angiography (CCTA) in diagnosing and managing coronary artery disease (CAD). The review highlights CCTA’s high sensitivity and negative predictive value in detecting coronary atherosclerosis in both stable and acute chest pain presentations.

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Serum Apo A-1 and Its Role as a Biomarker of Coronary Artery Disease

This 2016 case-control study evaluated the diagnostic performance of apolipoprotein A-1 (Apo A-1) compared to high-density lipoprotein (HDL) in detecting coronary artery disease (CAD). The study involved 100 angiographically confirmed CAD patients and 100 age- and sex-matched healthy controls. Results showed significantly lower mean Apo A-1 levels in CAD patients

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Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial

The ORBITA trial, a double-blind, randomized controlled study, evaluated the efficacy of percutaneous coronary intervention (PCI) compared to a placebo procedure in 200 patients with stable angina and significant single-vessel stenosis. After six weeks of medication optimization, results showed no significant difference in exercise time improvement between PCI and the

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